Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

ÀúÃâ·Â ·¹ÀÌÀú°¡ ±¸°­¹Ì»ý¹°¿¡ ¹ÌÄ¡´Â ¿µÇâ

Effect of Low-Level Laser to Oral Microorganisms

´ëÇѱ¸°­³»°úÇÐȸÁö 2010³â 35±Ç 1È£ p.31 ~ 39
À±ÀÎÁ¾, ¾î±Ô½Ä, Àü¾çÇö, È«ÁøÇ¥,
¼Ò¼Ó »ó¼¼Á¤º¸
À±ÀÎÁ¾ ( Yoon In-Jong ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
¾î±Ô½Ä ( Auh Q-Schick ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
Àü¾çÇö ( Chun Yang-Hyun ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
È«ÁøÇ¥ ( Hong Jung-Pyo ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç

Abstract

Ä¡ÁÖ¿°À̳ª ±¸Ãë¹ß»ý°ú °ü·ÃµÈ ±¸°­¹Ì»ý¹°¿¡ ´ëÇÑ ÀúÃâ·Â·¹ÀÌÀúÀÇ »ì±ÕÈ¿°ú¸¦ °üÂûÇϱâ À§ÇÏ¿©, Porphyromonas gingivalis 2561 (P. gingivalis 2561), Prevotella intermedia (Pr. intermedia)¿¡ ±¤°¨¼ö¼ºÁõ°¡¹°ÁúÀ» ó¸®ÇÔÀ¸·Î½á ½ÇÇè±ÕÁÖÀÇ ±¤¹Î°¨¼ºÀ» Áõ°¡½ÃŲ ÈÄ ÀúÃâ·Â·¹ÀÌÀú 650§¬ÀÇ ÆÄÀåÀ» ¿¬¼ÓÀûÀ¸·Î 1ºÐ, 2ºÐ, 3ºÐ, 5ºÐ°£, °¢°¢ 1§¯, 2§¯, 3§¯ °Å¸®¿¡¼­ Á¶»çÇÏ¿© ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù.
1. P. gingivalis 2561ÀÇ °æ¿ì Toluidine blue O(TBO) ó¸® ÈÄ 650§¬ÀÇ ÆÄÀåÀ¸·Î 3§¯ÀÇ °Å¸®¿¡¼­ 1ºÐ°£ Á¶»çÇÑ ½ÇÇ豺Àº TBO¸¸ ó¸®ÇÑ ½ÇÇè´ëÁ¶±º¿¡ ºñÇØ 99.99% ÀÌ»óÀÇ Ç×±ÕÈ¿°ú¸¦ ³ªÅ¸³»¾ú´Ù.
2. Pr. intermediaÀÇ °æ¿ì TBO ó¸® ÈÄ 650 §¬ÀÇ ÆÄÀåÀ¸·Î 3 §¯ÀÇ °Å¸®¿¡¼­ 1ºÐ°£ Á¶»çÇÑ ½ÇÇ豺Àº TBO¸¸ ó¸®ÇÑ ½ÇÇè´ëÁ¶±º¿¡ ºñÇØ 99.8% ÀÌ»óÀÇ Ç×±ÕÈ¿°ú¸¦ ³ªÅ¸³»¾ú´Ù.
3. P. gingivalis 2561ÀÇ °æ¿ì TBO ó¸® ÈÄ 650 §¬ÀÇ ÆÄÀåÀ» ¿¬¼ÓÀ¸·Î °¢°¢ 1ºÐ, 2ºÐ, 3ºÐ°£ Á¶»çÇÑ ½ÇÇ豺ÀÇ °æ¿ì ½Ã°£ÀÌ ±æ¾îÁú¼ö·Ï »ì±ÕÈ¿°ú°¡ Á¡Â÷ Áõ°¡µÇ¾ú´Ù.
4. P. gingivalis 2561ÀÇ °æ¿ì Á¶»ç°Å¸®°¡ 1 §¯, 2 §¯, 3 §¯À¸·Î Áõ°¡ÇÒ¼ö·Ï »ì±ÕÈ¿°ú°¡ ¾à°£ °¨¼ÒµÇ¾ú´Ù.
5. Pr. intermediaÀÇ °æ¿ì Á¶»ç°Å¸®°¡ 1 §¯, 2 §¯, 3 §¯À¸·Î Áõ°¡ÇÒ¼ö·Ï »ì±ÕÈ¿°ú°¡ ¾à°£ °¨¼ÒµÇ¾ú´Ù.
À§¿Í °°Àº °á°ú¸¦ ¹ÙÅÁÀ¸·Î ÀúÃâ·Â·¹ÀÌÀúÀÇ »ì±ÕÈ¿°ú´Â Á¶»ç½Ã°£ÀÌ ±æ¾îÁú¼ö·Ï, Á¶»ç°Å¸®°¡ ªÀ»¼ö·Ï »ì±ÕÈ¿°ú°¡ Áõ°¡µÇ¾ú´Âµ¥, »ì±ÕÈ¿°ú°¡ °¡Àå Àû°Ô ³ªÅ¸³­ 3 §¯ÀÇ °Å¸®¿¡¼­ 1ºÐ°£ Á¶»çÇÑ ½ÇÇ豺¿¡¼­µµ TBO¸¸ ó¸®ÇÑ °æ¿ìº¸´Ù 99.8% ÀÌ»óÀÇ »ì±ÕÈ¿°ú¸¦ ³ªÅ¸³»¾úÀ¸¹Ç·Î ÀúÃâ·Â·¹ÀÌÀúÀÇ ±¸°­¹Ì»ý¹°¿¡ ´ëÇÑ »ì±ÕÈ¿°ú´Â ¸í¹éÇÏ´Ù°í »ý°¢µÈ´Ù.
µû¶ó¼­ photosensitizerÀÇ ºÎÀÛ¿ëÀÌ ¾ø´Â ÇÑ°è ³»¿¡¼­ »ç¿ëÇÑ´Ù¸é ÀúÃâ·Â·¹ÀÌÀú°¡ Ä¡ÁÖ¿°, ÀÓÇöõÆ®ÁÖÀ§¿° µî¿¡ ´ëÇÑ º¸Á¶Àû Ä¡·á¿Í ±¸ÃëÁ¶Àý µî¿¡ ¸Å¿ì À¯¿ëÇÏ°Ô »ç¿ëµÇ¸®¶ó°í »ý°¢µÈ´Ù.

This study is to observe the bacteriocidal effect of the Low Level Laser (LLL) against oral microorganisms which are related to the occurrence of periodontal diseases and oral malodors. The Porphyromonas gingivalis 2561 (P. gingivalis 2561) and Prevotella intermedia (Pr. intermedia) were treated with photosensitizing substance-toluidine blue O (TBO; C.I. 52040) and then radiated with the LLL which has 650§¬ wavelength for 1, 2, 3 and 5mins. continuously upon varying distances of 1, 2 and 3§¯ for each experimental groups.
The results are as follows;
1. The P. gingivalis 2561 which was treated with TBO and then radiated with LLL at a distance of 3§¯ for 1min. showed 99.99% higher antibacterial effect in comparison to the experimental group treated only with TBO.
2. The Pr. intermedia which was treated with TBO and then radiated with LLL at a distance of 3§¯ for 1min. showed 99.8% higher antibacterial effect in comparison to the experimental group treated only with TBO.
3. The bacteriocidal effect of the P. gingivalis 2561 treated with TBO was found to gradually increase as the radiation time of LLL extended from 1min. to 3min. at 1min. intervals.
4. A slight decrease in bacteriocidal effect of the P. gingivalis 2561 was found as the radiation distance of LLL increased from 1§¯ to 3§¯ at 1§¯ intervals.
5. The bacteriocidal effect of the Pr. intermedia was found to slightly decrease as the radiation distance of LLL increased from 1§¯ to 3§¯ at 1§¯. intervals.
As the results shown above suggest, the bacteriocidal effect of LLL was found to increase as the radiation time extended and the distance shortened. Moreover, even the experimental group radiated with LLL at 3§¯ distance for 1min. which showed the lowest level of bacteriocidal effect, was found to have 99.8% higher bacteriocidal effect than the experimental group which was treated only with TBO and, therefore, this clearly shows the bacteriocidal effect of LLL against oral microorganisms.
Thus, the use of LLL is thought to become very useful for suportive treatment for periodontitis and implantitis, and controlling oral malodors as long as it is used within the limits where there is no side effect.

Å°¿öµå

ÀúÃâ·Â·¹ÀÌÀú;±¸°­¹Ì»ý¹°
P. gingivalis 2561;Prevotella intermedia;Low-Level Laser;Oral Microorganisms

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

  

µîÀçÀú³Î Á¤º¸

KCI